Modelling and set-point definition for the development of a joint control system of two interconnected wastewater treatment plants and its application in practice.

The use of activated sludge models (ASMs) is a common way in the field of wastewater engineering in terms of plant design, development, optimization, and testing of stand-alone treatment plants. The focus of this study was the development of a joint control system (JCS) for a municipal wastewater treatment plant (mWWTP) and an upstream industrial wastewater treatment plant (iWWTP) to create synergies for saving aeration energy. Therefore, an ASM3 + BioP model of the mWWTP was developed to test different scenarios and to find the best set-points for the novel JCS.

Patient involvement in diabetes-related foot ulcers: What do patients need and prefer when undergoing treatment at multidisciplinary outpatient foot centres? A phenomenological hermeneutic study.

We adopted a qualitative descriptive design to gain a broad understanding of the experiences, needs and preferences. Semi-structured interviews were conducted with 21 patients with diabetes-related foot ulcers using an interview guide. Patients were recruited from the four multidisciplinary foot centres in the Eastern Danish Region of Zealand.

Applying both the 30-s and the 5-repetition sit-to-stand tests captures dissimilar groups and a broader spectrum of physical abilities in mobility-limited older individuals: results from the BIOFRAIL study.

Purpose: We aimed to assess differences among older patients demonstrating low STS performance in the 30 s-STS and/or the 5r-STS.

Methods: 30 s-STS and 5r-STS were used to assess lower limb muscle strength and function in older adults. Analysis involved 376 patients (≥ 65 years) from a geriatric outpatient clinic for fall assessment.

The respiratory microbiome is linked to the severity of RSV infections and the persistence of symptoms in children.

Respiratory syncytial virus (RSV) is the leading cause of infant respiratory infections and hospitalizations. To investigate the relationship between the respiratory microbiome and RSV infection, we sequence nasopharyngeal samples from a birth cohort and a pediatric case-control study (Respiratory Syncytial virus Consortium in Europe [RESCEU]). 1,537 samples are collected shortly after birth ("baseline"), during RSV infection and convalescence, and from healthy controls.

Bacteria Engineered to Produce Serotonin Modulate Host Intestinal Physiology.

Bacteria in the gastrointestinal tract play a crucial role in intestinal motility, homeostasis, and dysfunction. Unraveling the mechanisms by which microbes impact the host poses many challenges due to the extensive array of metabolites produced or metabolized by bacteria in the gut. Here, we describe the engineering of a gut commensal bacterium, Nissle 1917, to biosynthesize the human metabolite serotonin for examining the effects of microbially produced biogenic amines on host physiology.