Publications by authors named "M T H M Henkens"
Article Synopsis
- The study investigates the prevalence and impact of inter-atrial block (IAB) as an indicator of electrical dysfunction in patients with heart failure with preserved ejection fraction (HFpEF).
- It examines two groups: ambulatory HFpEF patients and those recently hospitalized, assessing their risk for adverse events like hospitalization and death.
- Findings suggest that different stages of electrical atrial dysfunction significantly predict adverse outcomes, indicating that patients without dysfunction might require less intensive management.
Article Synopsis
- Systemic immune-mediated diseases (SIDs) may contribute to dilated cardiomyopathy (DCM), and this study aimed to explore the genetic predispositions present in DCM patients with SIDs.
- The research involved 183 DCM-SID patients, identifying a significantly higher prevalence of pathogenic genetic variants in these individuals compared to healthy controls and DCM patients without SIDs.
- Findings suggest that about 17-20% of DCM patients with SIDs have pathogenic variants, particularly truncating variants like TTN, indicating the importance of genetic testing for understanding the causes of immune-related DCM.
Quality of life and societal costs in patients with dilated cardiomyopathy.
Eur Heart J Qual Care Clin Outcomes
June 2024
Aims: Dilated cardiomyopathy (DCM) is a major cause of heart failure impairing patient wellbeing and imposing a substantial economic burden on society, but respective data are missing. This study aims to measure the quality of life (QoL) and societal costs of DCM patients.
Methods And Results: A cross-sectional evaluation of QoL and societal costs of DCM patients was performed through the 5-level EuroQol and the Medical Consumption Questionnaire and Productivity Cost Questionnaire, respectively.
Background: Collagen cross-linking is a fundamental process in dilated cardiomyopathy (DCM) and occurs when collagen deposition exceeds degradation, leading to impaired prognosis. This study investigated the associations of collagen-metabolism biomarkers with left ventricular function and prognosis in DCM.
Methods: DCM patients who underwent endomyocardial biopsy, blood sampling, and cardiac MRI were included.