Publications by authors named "M T Gussoni"

Background: Alcohol abuse is one of the most common causes of mortality worldwide. This study aimed to investigate the efficacy of a treatment in reducing circulating ethanol and oxidative stress biomarkers.

Methods: Twenty wine-drinking subjects were investigated in a randomized controlled, single-blind trial (ClinicalTrials.

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Intense, long exercise can increase oxidative stress, leading to higher levels of inflammatory mediators and muscle damage. At the same time, fatigue has been suggested as one of the factors giving rise to delayed-onset muscle soreness (DOMS). The aim of this study was to investigate the efficacy of a specific electrical stimulation (ES) treatment (without elicited muscular contraction) on two different scenarios: in the laboratory on eleven healthy volunteers (56.

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In this study, the metabolic responses of hypoxic breathing for 1 h to inspired fractions of 10% and 15% oxygen were investigated. To this end, 14 healthy nonsmoking subjects (6 females and 8 males, age: 32.2 ± 13.

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Exposure to acute normobaric hypoxia (NH) elicits reactive oxygen species (ROS) accumulation, whose production kinetics and oxidative damage were here investigated. Nine subjects were monitored while breathing an NH mixture (0.125 FO in air, about 4100 m) and during recovery with room air.

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Article Synopsis
  • Recent studies on Drosophila melanogaster reveal that genetic background significantly impacts lifespan and reactive oxygen species (ROS) levels under different oxygen conditions.
  • The research compared three wild-type lines (Canton-S, Oregon-R, and Berlin-K) and one mutant line (Sod1n1) under normoxic and hypoxic environments, using survival curves and ROS measurement techniques to analyze results.
  • Findings indicate that Canton-S flies are the most resilient to hypoxic stress with the lowest ROS increase, while Sod1n1 flies exhibited the shortest lifespan and highest ROS levels, suggesting a need for standardization in future research on lifespan and oxidative stress in Drosophila.
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