Publications by authors named "M T Gorris"
Study Question: How can we best achieve tissue segmentation and cell counting of multichannel-stained endometriosis sections to understand tissue composition?
Summary Answer: A combination of a machine learning-based tissue analysis software for tissue segmentation and a deep learning-based algorithm for segmentation-independent cell identification shows strong performance on the automated histological analysis of endometriosis sections.
What Is Known Already: Endometriosis is characterized by the complex interplay of various cell types and exhibits great variation between patients and endometriosis subtypes.
Study Design, Size, Duration: Endometriosis tissue samples of eight patients of different subtypes were obtained during surgery.
Primary hyperparathyroidism (PHPT) is underdiagnosed. Opportunistic imaging-based parathyroid gland assessment is a proposed strategy for identifying patients at increased risk of undiagnosed PHPT. However, whether this approach is likely to identify individuals with clinically significant disease is unknown.
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- Endoscopic retrograde cholangiopancreatography (ERCP) with fully covered self-expandable metal stent (FCSEMS) is the main method for biliary drainage in cases of suspected malignant biliary obstruction, but it carries a high risk of post-ERCP pancreatitis (PEP).
- A study aimed to compare the effects of performing an endoscopic sphincterotomy before FCSEMS placement versus not performing it at all on the incidence of PEP.
- The trial included 297 patients and found no significant difference in PEP rates between those who had the sphincterotomy and those who did not, leading to the conclusion that routine sphincterotomy is not necessary before FCSEMS placement
Article Synopsis
- This study investigates the effectiveness of adjuvant chemotherapy for patients with pancreatic ductal adenocarcinoma (PDAC) derived from intraductal papillary mucinous neoplasm (IPMN), highlighting the need for tailored treatment approaches due to limited evidence on this specific type of cancer.
- In a cohort of 1,031 patients, factors like nodal disease and elevated levels of carbohydrate antigen 19-9 (CA19-9) were linked to worse overall survival, with high-risk patients showing significant survival benefits from adjuvant chemotherapy.
- The findings suggest that a significant portion of patients (approximately 79.3%) are either overtreated or undertreated, emphasizing the
- Update articles supplement or update information found in full-length articles previously published in . These updates, written by at least one author of the previous article, provide a brief synopsis that emphasizes important new information such as technological advances, revised imaging protocols, new clinical guidelines involving imaging, or updated classification schemes.
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