Publications by authors named "M T G J Kumara"

Article Synopsis
  • Maternal morbidity and mortality, particularly due to uterine rupture, remain significant global health challenges, with this study focusing on its trends at Nekemte Specialized Hospital, Ethiopia.
  • Data from 2014 to 2022 showed a decline in uterine rupture cases from 1.54% to 0.93%, with an overall prevalence of 3.53% among 2661 participants.
  • Factors such as low household income, grandmultiparity, past obstetric complications, and previous cesarean sections were identified as significant associations with uterine rupture, indicating a need for better healthcare access and support for at-risk mothers.
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Article Synopsis
  • * Twelve in-depth and four key informant interviews were conducted and analyzed to identify six themes related to the diagnosis, challenges faced, and coping strategies among those affected.
  • * Key findings reveal that many women struggle to recognize early symptoms due to lack of awareness and preparation, leading to severe health consequences, and emphasize the importance of community education and improved access to healthcare for better outcomes.
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Objective: Walk With Ease (WWE) is an effective low-cost walking program. We estimated the budget impact of implementing WWE in persons with knee osteoarthritis (OA) as a measure of affordability that can inform payers' funding decisions.

Methods: We estimated changes in two-year healthcare costs with and without WWE.

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Objective: Randomized controlled trials (RCTs) are a gold standard for estimating the benefits of clinical interventions, but their decision-making utility can be limited by relatively short follow-up time. Longer-term follow-up of RCT participants is essential to support treatment decisions. However, as time from randomization accrues, loss to follow-up and competing events can introduce biases and require covariate adjustment even for intention-to-treat effects.

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Objective: To provide a framework for conducting clinical trial site visits virtually over videoconference, and to report on our experience doing so during the twelve-year follow-up of the Meniscal Tear in Osteoarthritis Research (MeTeOR) trial.

Design: Using published FDA guidance and prior literature, we created a structure for virtual site visits that prioritized monitoring for protocol compliance, safety, and data integrity. We conducted site visits in three stages: preparation for the visit, the virtual meeting itself, and follow-up.

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