Publications by authors named "M T Chernov"

Objective: To assess radiological characteristics that may support the clinical diagnosis of trigeminal neuralgia caused by pure venous conflict.

Methods: Preoperative constructive interference in steady state images were analyzed retrospectively in 30 patients with trigeminal neuralgia caused by pure venous conflict, which was confirmed during microvascular decompression. Length, width, T2 hyperintensity, and shape of the cisternal segment of trigeminal nerve (CN V), as well as sizes of the trigeminal-pontine angle, trigeminal-petrous angle, and cerebellopontine cistern were evaluated on both sides.

View Article and Find Full Text PDF
Article Synopsis
  • The blockage of miRNA biogenesis by proteins like LIN28 can lead to the activation of oncogenic genes, potentially fueling tumor growth and drug resistance.
  • Researchers have created a cell-based assay to find small molecules that boost mature let-7 miRNA levels by inhibiting LIN28B, using a system with a GFP reporter to track this process.
  • Screening around 4000 compounds, they identified several that increase miRNA levels and found that Kenpaullone and BIO effectively suppress MYCN protein in neuroblastoma cells, paving the way for new cancer drug screenings and potential therapeutic targets.
View Article and Find Full Text PDF

The aim of this study was to systematically review and meta-analyze the efficiency and safety of using the Robotic Stereotactic Assistance (ROSA) device (Zimmer Biomet; Warsaw, IN, USA) for stereoelectroencephalography (SEEG) electrode implantation in patients with drug-resistant epilepsy. Based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, a literature search was carried out. Overall, 855 nonduplicate relevant articles were determined, and 15 of them were selected for analysis.

View Article and Find Full Text PDF

Objective: To evaluate the incidence, associated factors, clinical course, and management options of subdural hygroma in patients treated for aneurysmal subarachnoid hemorrhage (aSAH).

Methods: From January 2013 until June 2022, 336 consecutive patients with aSAH underwent treatment in our center. No one patient was excluded from the study cohort.

View Article and Find Full Text PDF

Objective: Early (within 72 h) tumor-related hemorrhage (TRH) after stereotactic radiosurgery (SRS) of brain metastases (BM) has been reported only occasionally. Systematic review of such cases was done.

Methods: Literature search was performed through PubMed according to PRISMA guidelines using combination of the following medical subject headings: "hemorrhage," "stereotactic radiosurgery," and "brain metastasis.

View Article and Find Full Text PDF