Publications by authors named "M T Arredondo"

Article Synopsis
  • The study focuses on the herbaceous species PPL, which has bioactive compounds linked to anti-inflammatory properties, suggesting it might help with chronic inflammation conditions like inflammatory bowel diseases (IBD).
  • Researchers evaluated the effects of a PPL extract on inflammatory markers in Caco-2 cells, using a specific treatment setup and advanced characterization techniques like LC-MS/MS and qRT-PCR.
  • The findings indicated that PPL extract significantly reduced mRNA and protein levels of certain inflammatory markers after 72 hours of treatment, presenting PPL as a potential complementary therapy for improving the quality of life for IBD patients.
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  • Researchers developed a new low-temperature plasma-assisted method to create GdFeO nanoparticles from solid metallic foils of Gd and Fe, enabling both colloidal and thin film forms.
  • Characterization techniques like electron microscopy and spectroscopy confirmed the successful formation of the orthorhombic perovskite GdFeO phase and a uniform distribution of elements.
  • The nanoparticles displayed properties typical of antiferromagnetic materials, with potential applications in magnetic memory devices and gas sensors facilitated by a modified one-step thin film deposition process.
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  • The study investigates how bilingualism affects cognitive development among Mexican-origin bilingual youth who act as language brokers for their immigrant parents.
  • It explores the relationship between discriminatory experiences and cognitive control, specifically focusing on attentional control and inhibition in the context of their brokering activities.
  • Findings suggest that while discrimination does not directly impact cognitive control, its effects vary based on the youth's brokering experiences—less discrimination is linked to better cognitive control in those with positive bilingual experiences.
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TANGO2-deficiency disorder (TDD) is an autosomal-recessive genetic disease caused by biallelic loss-of-function variants in the TANGO2 gene. TDD-associated cardiac arrhythmias are recalcitrant to standard antiarrhythmic medications and constitute the leading cause of death. Disease modeling for TDD has been primarily carried out using human dermal fibroblast and, more recently, in Drosophila by multiple research groups.

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Article Synopsis
  • Spinocerebellar ataxia type 10 (SCA10) is a genetic disorder marked by an expansion of the (ATTCT)n repeat in the ATXN10 gene, primarily found in Native American and Asian populations.
  • Researchers discovered a common genetic marker (rs41524547-G) associated with SCA10, which is located near a miRNA gene and is largely limited to the Americas and East Asia.
  • The study suggests that this marker can help identify individuals at risk for SCA10 and supports the idea of a single ancestral origin for SCA10 expansions, possibly linked to migrations across the Bering Land Bridge.
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