The aim of the study was to determinate the serum leptin level, glucose concentration, lipids (total cholesterol, HDL-cholesterol, LDL-cholesterol, triglyceride) and thyroid hormones level (triiodothyronine, thyroid stimulating hormone and free thyroxine) in a group of prepubertal children with simple obesity. Fourfold higher leptin concentration in obese (23.3 +/- 11.
View Article and Find Full Text PDFThe project was realised within the multicentre research programme no PBZ038-08. In all, 2967 children aged 11-18 years were examined, including 1712 girls and 1255 boys. The tested children came from the Mazowieckie Voivodship.
View Article and Find Full Text PDFCongenital hypothyroidism occurs in 1:4000 newborns. Mass screening for congenital hypothyroidism constitutes a major progress in the prevention of mental retardation. The neonatal screening programme in Poland was established and implemented by the National Research Institute of Mother and Child from the middle of the 70.
View Article and Find Full Text PDFCongenital hypothyroidism is one of the most common diseases in paediatric endocrinology. Thyroid hormones are essential in brain development, which takes place during foetal life and early postnatal life up to the 2nd year of age. The main etiologic factors of congenital hypothyroidism are anomalies of development, function and regulation of the thyroid gland.
View Article and Find Full Text PDFEnlargement of the thyroid gland, local tenderness and thyroid function disorder are common symptoms of thyroiditis. Hashimoto's thyroiditis (chronic lymphocytic thyroiditis) is the most common form of thyroiditis in children. This disease is a frequent cause of acquired hypothyroidism.
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