Novel therapies in SLE treatment: A literature review.

Systemic lupus erythematosus (SLE) is a chronic, autoimmune inflammatory disease with a multisystem manifestation and a variety of clinical symptoms. Over the last decades, the prognosis and life expectancy of patients with SLE improved significantly due to the implementation of corticosteroids combined with immunosuppressive agents. Nevertheless, the use of these medications is often associated with the occurrence of serious side effects and additional deterioration of organ function.

Impact of Drill Bit Wear on Screw Withdrawal Resistance in Pinewood.

Many factors affect screw withdrawal resistance (SWR), including screw size, embedment depth, the pre-drilled hole's diameter, dimensional accuracy, and the furniture pieces' material properties being joined. While prior research has extensively examined the influence of these factors, this study aimed to explore a neglected factor: how drill bit wear impacts pilot hole quality and subsequent SWR. The experimental setup included pinewood samples with pre-drilled 5 mm diameter blind pilot holes with a depth of 45 mm.

Dataset on anthropometric measurements of the adult population in Slovakia.

This research on human body dimensions offers data for creating comfortable and efficient workplaces. Focusing on Slovak university students (2003-2023) as a representation of the adult population, the study measured 25 key anthropometric dimensions. 11355 respondents (5219 women and 6136 men) were selected for the analysis.

Mycelium-Based Composites: Surveying Their Acceptance by Professional Architects.

Mycelium-based composites (MBCs) are biomaterials with scientifically proven potential to improve sustainability in construction. Although mycelium-based products are not entirely new, their use in engineering presents challenges due to the inherent properties of this fungal material. This study investigated professional architects' and interior designers' perceptions of MBCs, focusing on familiarity, aesthetic appeal, and willingness to use.

The Application of Fluorescence Anisotropy for Viscosity Measurements of Small Volume Biological Analytes.

Time-resolved fluorescence anisotropy has been extensively used to detect changes in bimolecular rotation associated with viscosity levels within cells and other solutions. Physiological alterations of the viscosity of biological fluids have been associated with numerous pathological causes. This current work serves as proof of concept for a method to measure viscosity changes in small analyte volumes representative of biological fluids.