Publications by authors named "M Sundell"

Background: Because of the shift towards earlier diagnosis of dementia and/or Alzheimer's disease (AD), increasing numbers of individuals with subjective cognitive decline (SCD) and mild cognitive impairment (MCI) are seen in memory clinics. Yet, evidence indicates that there is room for improvement when it comes to tailoring of the diagnostic work-up to the needs of individual patients. To optimize the quality of care, we explored patients' perspectives regarding the diagnostic work-up at a specialized memory clinic.

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Background And Objective: Urologists are central to the coordinated care of patients with spina bifida (SB), and efforts to optimize bladder management and protection of the upper tracts are well established. However, the urologist's role in treating this population often extends to the management of bowel dysfunction which may be less defined. The methods available to the urologist for bowel management range from lifestyle modifications to medical and surgical therapy, with many patients requiring combinations of multiple strategies to combat conflicting symptoms of constipation and fecal incontinence (FI).

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Objective: To investigate the use of menopausal hormone therapy (MHT) in premenopausal women after bilateral oophorectomy.

Design: Retrospective register-based cohort study.

Setting: Sweden.

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Article Synopsis
  • The study analyzes trends in menopausal hormone therapy (MHT) usage among Swedish women aged 45-69 from 2000 to 2021, using individual-level data for 2.5 million women and aggregated sales volumes.
  • Key findings show that MHT use decreased by over 80% for women aged 50-54 until 2010, then stabilized, with a significant increase in incidence starting in 2017, especially among those nearing menopause.
  • The research concludes that an 18-month run-in period is effective for identifying first-time MHT users, highlighting that incidence rates are more responsive than prevalence rates or DDD in detecting prescription trend changes.
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Article Synopsis
  • Oral menopausal hormone therapy (MHT) raises the risk of pulmonary embolism (PE) in women, particularly among those who are first-time users.
  • A study involving over 1.7 million women revealed that current MHT users had a 15% higher risk of PE, with first-time users facing more than double the risk.
  • Transdermal MHT did not show an increased risk for PE, indicating it may be a safer option compared to oral administration.
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