Ergot alkaloids: comparison of extraction efficiencies for their monitoring in several cereal-solvent combinations by UPLC-MS/MS.

To date, there are more than 80 ergot alkaloids identified; their distribution depends on different factors (e.g. geographic regions, host plants).

Altered methylation of imprinted genes in neuroblastoma: implications for prognostic refinement.

Background: Neuroblastoma (NB) is a complex disease, and the current understanding of NB biology is limited. Deregulation in genomic imprinting is a common event in malignancy. Since imprinted genes play crucial roles in early fetal growth and development, their role in NB pathogenesis could be suggested.

Prompt Multi-level Segmentation with Denoising Model with Fragile Correlated Feature Subset for Brain Tumor Classification.

Background: Classifying brain tumors with extraordinary precision using images is critical for prognosis and treatment planning. The aberrant proliferation of brain cells characterizes brain tumors. Variations in neuronal development may occur among individuals.

Quantification of 700 mycotoxins and other secondary metabolites of fungi and plants in grain products.

This work reports on the validation of a liquid chromatography-tandem mass spectrometric method for the simultaneous quantification of more than 700 mycotoxins and other secondary fungal metabolites and plant toxins in pasta, biscuits, crackers and musli. The "dilute and shoot" approach was found to be fully applicable to these complex matrices, as only 7-14% of the analytes exhibited significant matrix effects while recoveries of the extraction were outside the target range of 70-120% for only 26 compounds. Data on repeatability (based on 7 brands per matrix) and on intermediate precision was compliant to the related < 20% criterion for 95-98% and 99% of all analytes, respectively.