The unseen perils of oral-care products generated micro/nanoplastics on human health.

The extensive use of plastics in modern dentistry, including oral care products and dental materials, has raised significant concerns due to the increasing evidence of potential harm to human health and the environment caused by the unintentional release of microplastics (MPs) and nanoplastics (NPs). Particles from sources like toothpaste, toothbrushes, orthodontic implants, and denture materials are generated through mechanical friction, pH changes, and thermal fluctuations. These processes cause surface stress, weaken material integrity, and induce wear, posing health risks such as exposure to harmful monomers and additives, while contributing to environmental contamination.

Metagenomic study of lake microbial mats reveals protease-inhibiting antiviral peptides from a core microbiome member.

In contrast to the large body of work on bioactive natural products from individually cultivated bacteria, the chemistry of environmental microbial communities remains largely elusive. Here, we present a comprehensive bioinformatic and functional study on a complex and interaction-rich ecosystem, algal-bacterial (microbial) mats of Lake Chilika in India, Asia's largest brackish water body. We report the bacterial compositional dynamics over the mat life cycle, >1,300 reconstructed environmental genomes harboring >2,200 biosynthetic gene clusters (BGCs), the successful cultivation of a widespread core microbiome member belonging to the genus , heterologous reconstitution of two silent biosynthetic pathways, and new compounds with potent protease inhibitory and antiviral activities.

Microplastics: The imperative influencer in blueprint of blue economy.

The burgeoning issue of microplastic pollution in marine ecosystems has emerged as a significant concern, presently multifaceted difficulty to the sustainability and prosperity of the blue economy. This review examines the intricate link between microplastics (MPs) and the blue economy (BE), exploring how microplastics infiltrate marine environments, their persistence, and their impacts on economic activities reliant on healthy oceans in a global scenario. Diminished seafood quality and quantity, degraded coastal aesthetics affecting tourism revenues, and increased operational costs due to fouling and contamination are among the economic repercussions identified.

Hormones in malaria infection: influence on disease severity, host physiology, and therapeutic opportunities.

Human malaria, caused by Plasmodium parasites, is a fatal disease that disrupts the host's physiological balance and affects the neuroendocrine system. This review explores how malaria influences and is influenced by hormones. Malaria activates the Hypothalamus-Pituitary-Adrenal axis, leading to increased cortisol, aldosterone, and epinephrine.

Intrinsic physiochemical insights to green synthesized Ag-decorated GO nanosheet for photoluminescence and in vivo cellular biocompatibility with embryonic zebrafish.

The advancement of nanotechnology and their application has intrigued a significant interest in green synthesis and application of organic and inorganic nanomaterials like graphene oxide (GO) and silver nanoparticles (AgNP). This study explores the intrinsic physiochemical properties of silver (Ag)-decorated graphene oxide (GO) nanosheets synthesized via a green approach, focusing on their photoluminescence behaviour and in vivo cellular biocompatibility with embryonic zebrafish. The nanocomposites were characterized using various spectroscopic and microscopic techniques to elucidate their structural and optical properties.