Publications by authors named "M Stuppe"

Article Synopsis
  • Disulfiram, although no longer approved for use in Germany over a decade ago, is still prescribed by many practitioners within the "Network for Alcohol Aversive Pharmacotherapy" (NAP), highlighting its ongoing relevance in treating alcoholism.
  • A survey conducted from 2019 to 2023 revealed that 1,579 treatment cases were reported, with 152 patients having drinking events, though most resulted in no serious complications.
  • The study found disulfiram to be generally well-tolerated, with common side effects including body odor and fatigue; importantly, many patients also had comorbid psychiatric conditions, and treatment often included additional therapies.
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Alcohol Use Disorder (AUD) is associated with reductions in grey matter (GM) volume which can lead to changes in numerous brain functions. The results of previous studies on altered GM in AUD differ considerably in the regions identified. Three meta-analyses carried out between 2014 and 2017 yielded different results.

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Background: In Europe, there have been several addiction-expert rankings of harms related to the use of psychotropic substances in the last 15 years. Among them, only one expert ranking took into account the potential benefits of these drugs. Non-Opioidergic Analgesics (NOAs), such as gabapentinoids and NSAIDs, which have been increasingly the subject of abuse / misuse reports, have not been considered in such expert rankings.

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Over the past 15 years, comparative assessments of psychoactive substance harms to both users and others have been compiled by addiction experts. None of these rankings however have included synthetic cannabinoids or non-opioid prescription analgesics (NOAs, e.g.

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Background And Aims: Existing evidence suggests that text message interventions can help people to reduce their alcohol consumption. However, studies with alcohol-dependent patients are lacking. In this study a 1-year automatic mobile phone-based short messaging service (SMS) intervention on alcohol consumption in patients after alcohol detoxification in hospital was compared with treatment as usual.

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