Publications by authors named "M Stojiljkovic"
The health-promoting benefits of walnut consumption are substantially ascribed to its fatty acid (FA) profile, which is rich in polyunsaturated FA with an exceptionally high n-3 to n-6 ratio. There are also phytonutrients in walnuts that are linked to health welfare. This review article integrates all studies on the effects of walnuts on the cardiovascular system performed on experimental animals, and thus is a source of data on the mechanisms underlying the observed effects.
View Article and Find Full Text PDFCancer-promoting proinflammatory microenvironment influences colorectal cancer (CRC) development. We examined the biomarkers of inflammation, intestinal differentiation, and DNA activity correlated with the clinical parameters to observe progression and prognosis in the adenocarcinoma subtype of CRC. Their immunohistology, immunoblotting, and RT-PCR analyses were performed in the adenocarcinoma and neighboring healthy tissues of 64 patients with CRC after routine colorectal surgery.
View Article and Find Full Text PDFArticle Synopsis
- Phenylketonuria (PKU) is a genetic disorder that leads to high levels of phenylalanine, causing cognitive issues if untreated, but the exact brain effects of this condition are still unclear.
- This study used a new model of NT2-derived neurons treated with varying concentrations of phenylalanine to investigate gene expression changes linked to PKU-related brain impairment.
- The research found that specific genes were altered in response to phenylalanine, affecting neuronal processes like dendrite and axon development, ultimately highlighting the neurotoxic effects of high phenylalanine levels.
Background: Critically ill COVID-19 patients are usually subjected to clinical, laboratory, and radiological diagnostic procedures resulting in numerous findings. Utilizing these findings as indicators for disease progression or outcome prediction is particularly intriguing.
Objectives: Exploring the significance of dynamic changes in haematological and biochemical parameters in predicting the mortality of critically ill COVID-19 patients.
Article Synopsis
- The study explored the use of next-generation sequencing (NGS) to identify genetic variants in 55 children with childhood epilepsy of unknown origins, ultimately diagnosing about 50.9% of the cases.* -
- Researchers found variants in 22 different epilepsy-associated genes, with significant findings related to SCN1A, ALDH7A1, and KCNQ2, which could inform targeted therapies for some patients.* -
- The discovery of novel genetic variants enhances the understanding of the genetic factors linked to childhood epilepsy and aims to improve diagnosis and treatment strategies globally.*