Publications by authors named "M Stilling"
Purpose: Spondylodiscitis is a serious condition requiring prolonged antibiotic therapy. Relevant pharmacokinetic tissue understanding of antibiotics in a spondylodiscitis setting is limited. The study aimed to investigate cefuroxime concentrations in the L4/L5 intervertebral disc, lumbar bone, paravertebral muscle and subcutaneous tissue using microdialysis.
View Article and Find Full Text PDFBackground: This study aimed to establish a feasible large porcine model for dynamic assessment of cisplatin concentrations in carcinomatosis-relevant abdominal tissues using microdialysis during and after HIPEC combined with cytoreductive surgery.
Methods: In total, eight pigs underwent open abdominal cytoreductive surgery followed by HIPEC. Microdialysis was employed for dynamic cisplatin concentration sampling in abdominal organs and tissue.
Anterior shoulder instability with glenoid bone lesion can be treated with the Eden-Hybinette procedure utilizing a tricortical iliac crest bone graft or the Latarjet procedure. This study aimed to evaluate the glenohumeral joint (GHJ) kinematics throughout an external shoulder rotation following the Eden-Hybinette and Latarjet procedures. Nine human specimens were examined with dynamic radiostereometry during a GHJ external rotation with anteriorly directed loads from 0 to 30 N.
View Article and Find Full Text PDFThis review aimed to summarize the current literature on antibiotic distribution in orthopedically relevant tissues and settings where dynamic sampling methods have been used. PubMed and Embase databases were systematically searched. English-published studies between 2004 and 2024 involving systemic antibiotic administration in orthopedically relevant tissues and settings based on dynamic measurements were included.
View Article and Find Full Text PDFArticle Synopsis
- - The study aimed to evaluate the wrist stabilizing effects and mechanical properties of four different materials used for wrist splints, including plaster of Paris (PoP), Woodcast, X-lite, and a 3D-printed polypropylene material.
- - Using cadaveric arm specimens, researchers tested how well each splint material resisted wrist flexion and extension under a controlled load, and they also conducted a bending test on samples of each material.
- - Results showed that PoP provided superior wrist stability and stiffness compared to the other materials, suggesting it may be the best option for wrist immobilization despite new alternatives like 3D printing.