Publications by authors named "M Stefanek"
Article Synopsis
- Biological aging is associated with changes in body composition and decreased levels of neuroactive steroid hormones, such as DHEAS, which have important roles in signaling.
- The study analyzed gut microbiota in mice to see how it affects lifespan, using advanced techniques like metagenomic sequencing and metabolic pathway analysis, finding specific bacteria correlated with longevity.
- Notably, long-lived mice had a higher presence of Bacteroides, linked to better lipid and steroid hormone metabolism, suggesting that gut bacteria contribute to healthier aging through cholesterol sulfate synthesis.
This work presents a comparative analysis of two clinical isolates of , isolated from haemoculture (HC) and central venous catheter (CVC). Both strains harboured Y132F and R398I mutations in the gene associated with resistance to fluconazole (FLC). Differences between the HC and CVC isolates were addressed in terms of virulence, resistance to FLC, and lipid distribution.
View Article and Find Full Text PDF, in recent years, has emerged as a dangerous nosocomial pathogen. It represents a challenge for effective treatment because of its multiresistance. Photodynamic inactivation (PDI) is a promising way to solve problems with a wide range of resistant microorganisms.
View Article and Find Full Text PDFBackground: The aim of this study was to analyze the relation between the hepatic fibrosis markers, liver morphology and hemodynamics assessed by magnetic resonance imaging (MRI) after total cavopulmonary connection (TCPC).
Materials And Methods: Adult patients after TCPC performed in childhood between 1993 and 2003 are the subjects of this observational study. The follow-up protocol consisted of clinical and echocardiographic examination, liver elastography, cardiopulmonary exercise test, MRI hemodynamics and liver morphology assessment and direct enhanced liver fibrosis (ELF) test.
Objective: The objective of this scoping review is to identify barriers and facilitators related to cancer clinical trial enrollment and participation among rural populations.
Introduction: Advancing the effectiveness of cancer treatment and increasing early detection of cancer relies on enrollment and participation of individuals in cancer clinical trials. Lack of enrollment and participation in trials is a concern, and there is evidence that individuals living in rural areas are unlikely to participate in such trials.