Publications by authors named "M Stals"

: Quality assurance in data collection is essential as data quality directly impacts the accuracy and reliability of outcomes. In the context of early detection of prostate cancer, improving data completeness is a key focus for enhancing patient care. This study aimed to evaluate the effectiveness of a data-driven feedback tool, visualized through a dashboard, in improving the completeness of data collection by healthcare professionals.

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Background: The recently published 4-level Pulmonary Embolism Clinical Probability Score (4PEPS) integrates different aspects from currently available diagnostic strategies to further reduce imaging testing in patients with clinically suspected pulmonary embolism (PE).

Aim: To externally validate the performance of 4PEPS in an independent cohort.

Methods: In this post-hoc analysis of the prospective diagnostic management YEARS study, the primary outcome measures were discrimination, calibration, efficiency (proportion of imaging tests potentially avoided), and failure rate (venous thromboembolism (VTE) diagnosis at baseline or follow-up in patients with a negative 4PEPS algorithm).

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Article Synopsis
  • * Researchers conducted a detailed meta-analysis involving 28,305 adult patients across various healthcare settings and developed a logistic regression model incorporating ten key predictors like age, sex, and previous medical history.
  • * The final model demonstrated high accuracy with a c-statistic of 0.87, showing it was more effective than existing algorithms (like the Wells score), although it slightly overestimated low probability cases.
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  • MCT8 deficiency is a rare disorder that significantly impacts daily caregiving, with a lack of comprehensive data on the complexities involved.
  • An international registry collected information from parents and physicians about the challenges faced by 51 registered patients, highlighting issues like feeding difficulties, limited motor skills, and sleep disturbances.
  • Key findings show late diagnoses and a need for better dietary guidance, particularly as underweight status is linked to poor survival rates; hence, there's a call for improved multidisciplinary care and outcomes measurement for affected patients.
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  • This study looked at how to safely check if pregnant women might have a serious condition called pulmonary embolism (PE) using different tests and rules.
  • They found that using the Wells rule and certain blood tests (D-dimer) can help figure out if PE is likely, and these methods worked well without too many false alarms.
  • However, another test using ultrasound on veins (CUS) didn’t work well unless the patients had more obvious symptoms of another condition, so it's better to use the blood tests in these cases.
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