Publications by authors named "M Stahnke"
Article Synopsis
- Anthracyclines, like Doxorubicin, are powerful anti-cancer drugs but can cause serious heart damage known as anthracycline-induced cardiotoxicity (AIC).
- A study using mice showed that AIC leads to systolic dysfunction and changes in the structure of the heart's left ventricle, with specific alterations in diffusion properties detectable by magnetic resonance imaging.
- The findings suggest that diffusion tensor imaging (DTI) could help in diagnosing and understanding the heart issues caused by AIC, calling for more research in clinical settings.
Background: Obesity exerts multiple deleterious effects on the heart that may ultimately lead to cardiac failure. This study sought to characterize myocardial microstructure and function in an experimental model of obesity-related cardiac dysfunction.
Methods: Male C57BL/6N mice were fed either a high-fat diet (HFD; 60 kcal% fat, = 12) or standard control diet (9 kcal% fat, = 10) for 15 weeks.
Objective: Full-field digital mammography (FFDM) has limited sensitivity for cancer in younger women with denser breasts. Digital breast tomosynthesis (DBT) can reduce the risk of cancer being obscured by overlying tissue. The primary study aim was to compare the sensitivity of FFDM, DBT and FFDM-plus-DBT in women under 60 years old with clinical suspicion of breast cancer.
View Article and Find Full Text PDFAim: To compare the diagnostic accuracy of standard screening images plus single-view digital breast tomosynthesis (DBT), using Siemens DBT equipment, with standard screening images plus supplementary mammographic views in non-calcific, screen-detected mammographic abnormalities.
Materials And Methods: Participants were unselected women aged 50-69 years recalled within a population-based European breast screening programme for assessment of soft-tissue mammographic abnormalities. Supplementary mammographic views (SMVs) and DBT were performed in all cases.
Radiopathological features predictive of involved margins in ductal carcinoma in situ.
Ann R Coll Surg Engl
February 2017
INTRODUCTION Ductal carcinoma in situ (DCIS) usually manifests as microcalcification on mammography but may be uncalcified. Consequently, a quarter of patients undergoing excision of a presumed pure DCIS require further surgery to re-excise margins. Patients at highest risk of margin involvement may benefit from additional preoperative assessment.
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