Early CRPS Is a Heterogeneous Condition: Results From a Latent Class Analysis.

Background: Complex regional pain syndrome (CRPS) is a debilitating condition characterised by significant heterogeneity. Early diagnosis is critical, but limited data exists on the condition's early stages. This study aimed to characterise (very) early CRPS patients and explore potential subgroups to enhance understanding of its mechanisms.

Complications of Post-Roux-en-Y Gastric Bypass: A Case of Excluded Stomach Perforation.

Roux-en-Y gastric bypass (RYGB) is a common surgical treatment for morbid obesity, but rare complications involving the excluded gastric remnant can pose significant challenges. A 65-year-old female with a history of RYGB presented with sudden onset of left upper quadrant abdominal pain, bloating, nausea, and loss of appetite. Laboratory tests revealed leukocytosis.

The Role of Empiric Antifungal Therapy in Patients With Perforated Peptic Ulcer: An Updated Systematic Review and Meta-Analysis.

Fungal growth is common in intraoperative cultures of patients with perforated peptic ulcer (PPU) leading to the common use of empiric antifungal therapy, with current evidence not clearly supporting this practice. The goal of this updated systematic review and meta-analysis was to synthesize the effect of empiric antifungals in patients with PPU. Eligible studies were identified through a comprehensive literature search in the MEDLINE (PubMed) and EMBASE databases, following the PRISMA 2020 statement.

Artificial Intelligence-Driven Advances in Coronary Calcium Scoring: Expanding Preventive Cardiology.

Coronary artery disease (CAD) remains a leading global cause of morbidity and mortality, underscoring the need for effective cardiovascular risk stratification and preventive strategies. Coronary artery calcium (CAC) scoring, traditionally performed using electrocardiogram (ECG)-gated cardiac computed tomography (CT) scans, has been widely validated as a robust tool for assessing cardiovascular risk. However, its application has been largely limited to high-risk populations due to the costs, technical requirements, and limited accessibility of cardiac CT scans.

Should Mesh Plug Use Be Discontinued in Hernia Repair Practices?

Mesh plugs are commonly used in inguinal hernia repair due to their perceived efficacy in reducing recurrence rates. However, their use has been associated with significant complications, including mesh migration, chronic pain, infection, hernia recurrence, adhesions, and erosion into adjacent organs. This case series presents three patients who experienced complications from mesh plug migration post-hernia repair.