Highly sensitive, selective, and compact hydrogen (H) sensors for safety and process monitoring are needed due to the growing adoption of H as a clean energy carrier. Current resonant frequency-based H sensors face a critical challenge in simultaneously achieving high sensitivity, low operating frequency, and miniaturization while maintaining a high figure of merit (FOM). This study addresses these challenges by introducing a novel piezoelectric micro diagram (PMD) H sensor that achieves an unprecedented FOM exceeding 10.
View Article and Find Full Text PDFPolymeric particles, particularly poly(lactic--glycolic acid) nanoparticles (PLGA NPs), have gained widespread utility in drug delivery, including their incorporation into established clinical formulations. However, their significance is enhanced when loaded with perfluorocarbons (PFCs). This integration enables precise imaging and quantification using advanced techniques such as F nuclear magnetic resonance (NMR) or magnetic resonance imaging.
View Article and Find Full Text PDFRapid advancements in long-read sequencing have facilitated species-level microbial profiling through full-length 16S rRNA sequencing (~ 1500 bp), and more notably, by the newer 16S-ITS-23S ribosomal RNA operon (RRN) sequencing (~ 4500 bp). RRN sequencing is emerging as a superior method for species resolution, exceeding the capabilities of short-read and full-length 16S rRNA sequencing. However, being in its early stages of development, RRN sequencing has several underexplored or understudied elements, highlighting the need for a critical and thorough examination of its methodologies.
View Article and Find Full Text PDFMyopic eye growth induces mechanical stretch, which can lead to structural and functional retinal alterations. Here, we investigated the effect of lens-induced myopic growth on the distribution of retinal ganglion cells (RGCs), glial fibrillary acidic protein (GFAP) expression and intensity, and peripapillary retinal nerve fiber layer (ppRNFL) thickness in common marmosets () induced with myopia continuously for six months, using immunohistochemistry and spectral-domain optical coherence tomography. We also explored the relationship between cellular structural parameters and the photopic negative response (PhNR) using full-field electroretinography.
View Article and Find Full Text PDFIntroduction Parkinson's disease (PD) is primarily thought to be brought on by the death of dopaminergic neurons in the substantia nigra pars compacta of the basal ganglia. Communication difficulties are a common symptom of PD, affecting both motor speech and language systems. These challenges significantly impact the quality of life by reducing participation in communication, leading to social withdrawal, and increasing the risk of social isolation and stigma among individuals with PD.
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