Publications by authors named "M Sponza"
Background: Although mechanical thrombectomy (MT) represents the standard of care for ischemic stroke due to large-vessel occlusion (LVO), the impact of sex on outcomes in tandem occlusions remains unclear. We investigated sex-based differences in outcomes after MT for tandem occlusions.
Methods: This multicenter observational study included consecutive patients with tandem occlusion treated with MT across three stroke centers (2021-2023).
Background And Objectives: The optimal mechanical thrombectomy technique for distal, medium vessel occlusion (DMVO) stroke remains unknown. We aimed to compare the safety and efficacy of 2 thrombectomy first-line approaches, direct aspiration (DA), and combined technique (CT) in patients with DMVOs.
Methods: We conducted a retrospective review of a prospectively collected multicenter database of patients with DMVOs (at or distal to M2 and A1), who underwent mechanical thrombectomy with JET D reperfusion catheters between January 2020 and December 2021.
Article Synopsis
- A study aimed to compare outcomes of general anesthesia (GA) versus non-general anesthesia (non-GA) in patients aged 90 and older undergoing mechanical thrombectomy (MT) for acute ischemic stroke, a group often excluded from previous research.
- The analysis included 139 patients, with those receiving non-GA showing significantly worse outcomes in 90-day modified Rankin Scale (mRS) scores and higher mortality rates.
- The findings suggest that nonagenarians treated with MT without GA have poorer prognoses, highlighting the need for further research on anesthesia techniques for this age group.
Neuroradiological manifestations in hospitalized patients with COVID-19: An Italian national multicenter study on behalf of AINR (Associazione Italiana di Neuroradiologia) and SIRM (Società Italiana di Radiologia Medica).
Neuroradiol J
June 2024
Article Synopsis
- This multicentric study investigated neuroradiological findings in COVID-19 patients during the early pandemic in Italy, focusing on data collected from May to June 2020 at two hospitals.
- A total of 415 patients were enrolled, with notable findings including ischemic stroke (29.4% of patients) and a variety of non-stroke neuroimaging lesions like PRES-like syndrome and encephalitis.
- The study concluded that COVID-19 patients are at increased risk of strokes due to a pro-thrombotic environment, reinforcing findings observed globally regarding brain imaging in infected patients.
Background: There is a lack of data regarding patients aged 90 years or older undergoing mechanical thrombectomy and their predictors of futile recanalization.
Aims: We sought to evaluate the predictors of futile recanalization in patients ≥ 90 years with large vessel occlusion undergoing mechanical thrombectomy.
Methods: This multi-center observational retrospective study included patients ≥ 90 years consecutively treated with mechanical thrombectomy in four thrombectomy capable centers between January 1st, 2016 and 30th March 2023.