Exploring narrative feedback to undergraduate dental hygiene and dental therapy students.

Purpose/objectives: The nature and quality of feedback provided during the training of healthcare students have been found to influence the progress of students throughout their clinical practice. The use of electronic systems for feedback is becoming more prevalent; but there appears to be an absence of research into the use of these systems with Dental Hygiene and Dental Therapy students (DHDT). The aim of this study was to explore the written, narrative feedback provided by tutors to undergraduate DHDT students on a 3-year BSc programme, using Liftupp - an Information Management System that incorporates electronic feedback mechanisms.

A retrospective clinical study on the survival of posterior composite restorations in a primary care dental outreach setting over 11years.

Objectives: To investigate the survival in terms of time to re-intervention of composite restorations in posterior teeth among patients attending for treatment at a primary care dental outreach setting over an 11-year period and to determine whether dental, patient or operator factors influenced this.

Methods: Electronic primary dental care data were collected on individual patients, including information on their dental treatment and socio-demographics as well as service provision, key performance indicators and student activity.

Results: A total of 1086 patients had at least one posterior composite placed between 2007 and 2018.

Zebrafish Embryo Model for Assessment of Drug Efficacy on Mycobacterial Persisters.

Tuberculosis continues to kill millions of people each year. The main difficulty in eradication of the disease is the prolonged duration of treatment, which takes at least 6 months. Persister cells have long been associated with failed treatment and disease relapse because of their phenotypical, though transient, tolerance to drugs.

Cell envelope stress in mycobacteria is regulated by the novel signal transduction ATPase IniR in response to trehalose.

The cell envelope of mycobacteria is a highly unique and complex structure that is functionally equivalent to that of Gram-negative bacteria to protect the bacterial cell. Defects in the integrity or assembly of this cell envelope must be sensed to allow the induction of stress response systems. The promoter that is specifically and most strongly induced upon exposure to ethambutol and isoniazid, first line drugs that affect cell envelope biogenesis, is the iniBAC promoter.

iniBAC induction Is Vitamin B12- and MutAB-dependent in Mycobacterium marinum.

Tuberculosis can be treated with a 6-month regimen of antibiotics. Although the targets of most of the first-line antibiotics have been identified, less research has focused on the intrabacterial stress responses that follow upon treatment with antibiotics. Studying the roles of these stress genes may lead to the identification of crucial stress-coping mechanisms that can provide additional drug targets to increase treatment efficacy.