Publications by authors named "M Sonoda"
Background: Pit pattern diagnosis using crystal violet staining for colorectal tumors is useful for qualitative and depth diagnosis. However, due to its reported carcinogenic potential, the use of crystal violet has been restricted. This study was aimed at investigating the efficacy of texture and color enhancement imaging (TXI) magnification in pit pattern diagnosis.
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- Neonatal protein C deficiency can lead to severe conditions like purpura fulminans and has a generally poor prognosis, especially regarding vision.
- In a study of 38 survivors with biallelic PROC variants, a significant number suffered from severe visual impairments: 23 were totally blind, and only one had normal vision.
- Prenatal intervention is crucial to enhance visual outcomes, as ocular lesions often present early in these cases, affecting the eyes before other organs.
Purpose: The purpose of this study is to investigate the potential of deep learning (DL) techniques to enhance the image quality of low-field knee MR images, with the ultimate goal of approximating the standards of high-field knee MR imaging.
Methods: We analyzed knee MR images collected from 45 patients with knee disorders and six normal subjects using a 3T MR scanner and those collected from 25 patients with knee disorders using a 0.4T MR scanner.
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- Evolocumab, a monoclonal antibody approved for treating familial hypercholesterolemia (FH) and hypercholesterolemia, was evaluated in a real-world study in Japan, as data on its effectiveness and safety were previously limited.
- The study involved 3724 patients with various forms of FH and hypercholesterolemia over 104 weeks, measuring both safety (incidences of adverse reactions) and effectiveness (changes in LDL cholesterol levels).
- Results indicated that Evolocumab was well tolerated, showing significant reductions in LDL cholesterol levels, with low rates of serious adverse events, suggesting it is a viable treatment option for high-risk patients in Japan.
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- Malrotation is a congenital condition that can lead to serious bowel issues, often diagnosed by age 1, but can sometimes be identified prenatally through imaging techniques.
- A 30-year-old woman had her routine ultrasound reveal signs of malrotation in her fetus, confirmed postnatally, leading to a successful laparoscopic surgery called the Ladd's procedure shortly after birth.
- This case shows that malrotation can indeed be spotted before birth and that preventive surgery can be safely done in newborns, reducing the risk of complications like midgut volvulus.