Oral lesions are common in dogs and cats, and determining the underlying etiology of these lesions can be challenging. A wide range of systemic ailments may lead to lesions in the oral cavity, including immune-mediated diseases, adverse drug reactions, viral and bacterial infections, and metabolic and autoimmune diseases. A complete history and thorough physical examination (including a fundic examination) should be obtained in affected patients.
View Article and Find Full Text PDFObjective: Canine oral neoplasia is often detected late in the course of the disease, necessitating radical surgeries frequently combined with adjuvant chemotherapy or radiotherapy for positive outcomes. Although there has been extensive analytical and epidemiologic work on human oral cancer, research in veterinary medicine has been lacking. This study aimed to evaluate the prevalence and risk factors associated with canine oral neoplasia to enhance early detection by improving screening.
View Article and Find Full Text PDFIntroduction: The purpose of this study was to evaluate the use of a novel imaging modality, digital tomosynthesis (DT), for identification of predefined anatomic dental and maxillomandibular structures in dogs.
Methods: DT images were compared to conventional intraoral dental radiography (DR) for the diagnostic yield regarding the presence and quality of visualization of 35 structures. DT imaging and full mouth DR were obtained on 16 canine cadaver heads and a semi-quantitative scoring system was used to characterize the ability of each imaging method to identify the anatomic structures.
Pre-determined anatomical locations in the oral cavity were biopsied, and their histomorphology was characterised using haematoxylin and eosin staining (H&E). The most abundant cell type was of dendritic morphology. Lymphocyte foci were not evident in the palatoglossal folds or the gingiva.
View Article and Find Full Text PDFIntroduction: The objective of this study was to investigate the diagnostic potential of bacterial biomarkers by comparing the performance of molecular detection assays with clinical assessments of dog's oral health performed by veterinarians.
Methods: Supragingival and subgingival plaque samples were collected from 127 client-owned dogs, pre-booked for procedures under general anesthesia, visiting veterinary practices in the United States. DNA was extracted and bacterial biomarkers quantified using quantitative polymerase chain reaction.