Publications by authors named "M Sofia Nuncio"

Mpox is a zoonotic disease caused by the Monkeypox virus (MPXV), and since May 2022, tens of thousands of cases have been reported in non-endemic countries. We aimed to evaluate the suitability of different sample types for mpox diagnostic and assess the temporal dynamics of viral load. We evaluated 1914 samples from 953 laboratory-confirmed cases.

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Tick-borne pathogens are a worldwide threat to public health that can only be mitigated by knowledge on tick-host associations coupled with surveillance of their infection by pathogenic microorganisms. This information is not equally available throughout tick vector distribution range and is deficient in some geographical areas. In this study we did a molecular survey of tick-borne pathogens associated with different tick species in Morocco.

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Article Synopsis
  • * The study employed a SEIR model to analyze transmission dynamics and found that MSM with high sexual activity contributed significantly more to mpox spread than those with low sexual activity, but vaccinated individuals were less likely to spread the virus.
  • * Findings suggest that ongoing vaccination efforts, increased awareness in at-risk communities, and regular genomic surveillance are essential for managing future mpox outbreaks and potential threats from new viral clades.
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  • Lyme disease, caused by spirochete bacteria transmitted by ticks, is the most common and rapidly spreading tick-borne illness in Europe and North America.
  • Researchers sequenced the genomes of 47 Lyme disease isolates, revealing a diverse range of species and consistent plasmid features that are crucial for the bacteria's adaptation.
  • The study highlights the genetic complexities involved, such as recombination and rapid evolution, especially in genes that interact with hosts, contributing to the bacteria's virulence while maintaining a mostly clonal population structure.
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  • Mpox, caused by the monkeypox virus, transitioned from primarily animal-to-human transmission to significant human-to-human sexual transmission during the 2022 global outbreak.
  • Researchers investigated the epidemiology and clinical features of 291 patients with mpox, revealing that 107 patients also had a total of 169 other sexually transmitted infections (STIs).
  • The study highlights the importance of comprehensive medical histories and complete STI screenings for those diagnosed with or suspected to have mpox.
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