Publications by authors named "M Sniegocki"
Resveratrol, a naturally occurring polyphenolic compound found in various plants, has been extensively studied for its broad spectrum of beneficial biological effects. These encompass its potent antioxidant properties, anti-inflammatory activities, anti-aging capabilities, cardioprotective functions, and neuroprotective potential. The diverse biological actions of resveratrol extend beyond these well-established properties.
View Article and Find Full Text PDFA natural compound derived from the Pausinystalia yohimbe tree-yohimbine, has a rich history of use in traditional medicine and is currently being explored for its potential therapeutic applications. This indole alkaloid primarily acts as an antagonist of α2-adrenergic receptors. Initially recognized for its purported aphrodisiac properties, yohimbine has been investigated for a wide range of applications, including sports or the treatment of erectile dysfunction and metabolic disorders.
View Article and Find Full Text PDFBrain tumors account for 1% of all cancers diagnosed de novo. Due to the specificity of the anatomical area in which they grow, they can cause significant neurological disorders and lead to poor functional status and disability. Regardless of the results of biochemical markers of intracranial neoplasms, they are currently of no diagnostic significance.
View Article and Find Full Text PDFArticle Synopsis
- Melanoma is a type of skin cancer linked to ultraviolet radiation, has a high mortality rate, and its progression to brain metastases severely impacts patient prognosis.
- Up to 50% of metastatic melanoma cases contain a BRAF mutation, aiding in the cancer's survival and development in the brain.
- Current research is focused on improving treatment outcomes through immunotherapy and targeted therapies, with ongoing studies summarizing the effectiveness of these new systemic treatments for brain metastases.
Article Synopsis
- Intracranial hemorrhage linked to meningiomas is uncommon, accounting for about 1% of cases; it can occur within the tumor or on its surface, potentially leading to severe complications like increased intracranial pressure.
- Between 2006 and 2020, three patients with meningioma-related hemorrhage were surgically treated in our department, with one emergency case and two planned surgeries, all resulting in favorable outcomes.
- All three hemorrhages were associated with WHO I convexity meningiomas, and despite some literature suggesting higher risks in more malignant tumors, our findings align with existing data on the mechanisms of bleeding and incidence rates.