Publications by authors named "M Smorczewska"
Article Synopsis
- Primary mediastinal B-cell lymphoma (PMBL) has a high cure rate of 85-95%, with various treatment regimens including RCHOP and DAEPOCH-R; this study examined a protocol involving aggressive immunochemotherapy and intermediate-dose methotrexate.
- The study involved 124 patients, with a median follow-up of 9 years, showing impressive 5-year overall survival (94%) and progression-free survival (92%), influenced by PET-CT results post-chemotherapy.
- The intensive treatment showed low rates of severe side effects (0.8% treatment-related mortality) and late toxicities (2.4% for second malignancies and cardiotoxicity), indicating its effectiveness and safety in young
The incidence of brain metastases in small cell lung cancer patients in the group without prophylactic cranial irradiation (PCI) was compared with the incidence of brain secondaries after PCI. Out of 29 patients without brain irradiation 13 patients experienced brain metastases at 19 months (13/29). On the contrary, no one out of 17 patients who received PCI was found to have brain metastases at 4 years.
View Article and Find Full Text PDFBetween Nov. 1981 and Nov. 1987 103 patients preselected for chemotherapy combined with surgery, therefore with local extension within homolateral mediastinal lymph nodes, with no signs of remote metastases, PS greater than or equal to 70, with no contraindication for resectional surgery including pneumonectomy, no diabetes, no prior treatment underwent first staging.
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