Publications by authors named "M Slon"
Article Synopsis
- The study explores the impact of COVID-19 on patients with glomerulonephritis (GN) by analyzing data from 125 GN patients and 83 non-GN controls, focusing on kidney health outcomes over an average follow-up period of 6.4 months.
- Findings indicate that there were no significant differences in mortality or acute kidney injury (AKI) between GN patients and controls, with pre-COVID-19 kidney function (eGFR) being a critical predictor of AKI risk.
- GN patients show a lower likelihood of recovering kidney function post-AKI compared to controls, particularly those with shorter GN diagnoses or higher protein levels, suggesting a need for careful monitoring of these patients after COVID-19.
Article Synopsis
- The study investigated the impact of COVID-19 on patients with immune-mediated glomerulonephritis, who are typically on immunosuppressive treatments, by creating the International Registry of COVID infection in glomerulonephritis (IRoc-GN) and examining 40 affected individuals alongside 80 matched controls.
- Findings revealed that patients with glomerulonephritis experienced significantly higher mortality rates (15%) and acute kidney injury (39%) compared to controls (5% and 14%, respectively), although the need for kidney replacement therapy was similar between the two groups.
- Key risk factors linked to worse outcomes in glomerulonephritis patients included lower serum albumin levels and shorter disease duration at the time
[Secondary glomerulonephritis in neurofibromatosis type 1. Two case reports].
An Sist Sanit Navar
December 2019
Neurofibromatosis type 1 (NF-1) is an autosomal dominant neurocutaneous disorder with systemic clinical manifestations. There are few publications about the renal effects of this disease, with renal vascular disease and adrenal tumors being the most frequent forms of renal involvement, while cases describing glomerular effects are exceptional. Despite the lack of published information, common molecular mechanisms in both NF-1 and nephrotic syndrome, involving the mTOR pathway, were suggested to explain a possible association between both pathologies.
View Article and Find Full Text PDFBackground: Utilization of home hemodialysis (HHD) is low in Europe. The Knowledge to Improve Home Dialysis Network in Europe (KIHDNEy) is a multi-center study of HHD patients who have used a transportable hemodialysis machine that employs a low volume of lactate-buffered, ultrapure dialysate per session. In this retrospective cohort analysis, we describe patient factors, HHD prescription factors, and biochemistry and medication use during the first 6 months of HHD and rates of clinical outcomes thereafter.
View Article and Find Full Text PDF