Clinical management of secondary angiosarcoma after breast conservation therapy.

Aim: The aim of this paper is to summarize the treatment outputs of secondary angiosarcoma after breast conservation therapy at St. Eizabeth Cancer Centre, Slovakia.

Background: Angiosarcoma of the breast is a rare but very aggressive malignant tumor of the vascular endothelium, characterized by rapidly proliferating and extensively infiltrating growth.

Late effects of breast-feeding and early weaning: seven-year prospective study in children.

The effect of breast feeding on some clinical and thyroid function parameters was studied in a prospective longitudinal study from birth up to 7 years of age. At the ages 1-7 years, the obesity rates observed in children breast-fed for less than 3 months were substantially higher than in children who had been breast-fed over longer intervals. Mean age when obesity was reported was similar in all groups (4-5 years).

[Lipoprotein profiles in 6-year-old children breast fed for different periods of time].

The authors submit results of investigations of the lipoprotein profile in six-year-old children fed a different diet during infancy. It is the continuation of previous results of a long-term longitudinal investigation of this group of healthy children which revealed a favourable effect of breastfeeding on the cholesterol distribution in lipoprotein fractions. Throughout the investigation the children were divided into four groups according to the breastfeeding period.

[Pfeiffer's syndrome].

The authors examined a 2-month-old infant with clinical signs of Pfeiffer's syndrome (craniosynostosis, abnormalities of the extremities, normal psychomotor development). In the family other affected cases were revealed with a variable expressivity of the clinical signs. The authors draw attention to the importance of a detailed clinical, X-ray and anthropometric examination of different members of the family to detect carriership of the gene for ACS.

[The effect of different types of infant nutrition on indicators of lipid metabolism in 1-to-4-year-old children].

The authors present the results obtained in investigations of the influence of different infant diets on some indicators of lipid metabolism in a group of healthy children followed up from birth and aged 1-4 years at the time of the investigation. The work is a continuation of previous investigations which provided evidence of the influence of breastfeeding on blood lipid levels and the cholesterol distribution in different lipoprotein fractions during the early postnatal period. The analysis of the plasma cholesterol and lipoprotein cholesterol in children breastfed for varying periods and children not breastfed bottlefed) at the age of 1, 1.