Publications by authors named "M Skrap"

Background/objectives: Ventriculoperitoneal shunting is a validated procedure for the treatment of idiopathic normal-pressure hydrocephalus. To select shunt-responsive patients, infusion and tap tests can be used. Only gait is evaluated after the procedure to establish a potential improvement.

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Background: Tractography allows the in vivo study of subcortical white matter, and it is a potential tool for providing predictive indices on post-operative outcomes. We aim at establishing whether there is a relation between cognitive outcome and the status of the inferior fronto-occipital fasciculus's (IFOF's) microstructure.

Methods: The longitudinal neuropsychological data of thirty young (median age: 35 years) patients operated on for DLGG in the left temporo-insular cortex along with pre-surgery tractography data were processed.

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Purpose: Patients diagnosed with High Grade Gliomas (HGG) generally tend to have a relatively negative prognosis with a high risk of early tumor recurrence (TR) after post-operative radio-chemotherapy. The assessment of the pre-operative risk of early versus delayed TR can be crucial to develop a personalized surgical approach. The purpose of this article is to predict TR using MRI radiomic analysis.

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We explored the functional outcome following awake surgery and Real-Time Neuropsychological Testing (RTNT) in the left insula. We carried out a longitudinal investigation by comparing the patients' language profile, and, in particular, the object-naming skills and the associated fMRI network, of pre-surgery and follow-up (i.e.

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Article Synopsis
  • Long-standing overt ventriculomegaly in adults (LOVA) can cause cognitive deficits, but studies on its cognitive impact and the effectiveness of endoscopic third ventriculostomy (ETV) are limited.
  • In a study with 23 LOVA patients, cognitive assessments before, after, and five months following ETV revealed selective long-term memory and visuospatial skill deficits, but no overall cognitive decline.
  • ETV surgery led to significant improvements in these areas, particularly in patients with higher premorbid IQ, suggesting that cognitive reserve plays a crucial role in brain plasticity and recovery following surgery.
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