Publications by authors named "M Skally"
Article Synopsis
- Community-associated infections (CA-CDI) have been rising globally, with definitions based on symptom onset timing and prior hospital stays affecting classification.
- A study of new CDI cases from 2012-2021 aimed to evaluate different methods of categorizing patients to better understand their CDI origin and improve surveillance.
- Results showed that changing the criteria for defining types of CDI led to significant shifts in patient classification, emphasizing the need for updated guidelines to enhance prevention strategies.
Clostridioides difficile infection (CDI) remains a significant cause of morbidity and mortality worldwide. Historically, two antibiotics (metronidazole and vancomycin) and a recent third (fidaxomicin) have been used for CDI treatment; convincing data are now available showing that metronidazole is the least efficacious agent. The European Society of Clinical Microbiology and Infectious Diseases (ESCMID) management guidance for CDI were updated in 2021.
View Article and Find Full Text PDFBackground: Clostridioides difficile infection (CDI) is a leading cause of healthcare-associated (HA) diarrhoea, contributing to patient morbidity and prolonged length-of-stay (LOS). We retrospectively assessed CDI over a decade in a national neurosurgical centre, with a multi-disciplinary approach to CDI surveillance and antimicrobial stewardship, by comparing CDI patients with other patient groups.
Methods: Data on CDI in neurosurgical inpatients between January 2012 and December 2021 were collated.
Introduction: Clostridioides difficile infection (CDI) is a leading cause of healthcare-associated (HA) diarrhoea. We retrospectively investigated data from a comprehensive, multidisciplinary C. difficile surveillance programme focusing on hospitalized patients in a tertiary Irish hospital over 10 years.
View Article and Find Full Text PDFBackground: In an era of increasing antimicrobial resistance, appropriate antimicrobials are essential to optimise patient outcomes. In 2017, antimicrobial use prevalence (AMU) on the two neurosurgical wards in our tertiary teaching hospital varied from 23% on ward A to 33% on ward B with 67% and 100% 'appropriate' prescriptions, respectively. In July 2018, a weekly antimicrobial stewardship multidisciplinary round led by a senior neurosurgery registrar commenced, attended by the antimicrobial stewardship team (AST).
View Article and Find Full Text PDF