Publications by authors named "M Sivalingam"
Purpose: To determine the outcomes of sickle cell retinopathy (SCR) patients who experienced at least one episode of being lost to follow-up (LTFU) compared to those who attended all appointments.
Methods: Adult SCR patients who visited Wills Eye Hospital Retina service (January 2012-December 2021) with >2 visits were reviewed for LTFU events, defined as failure to return for a follow-up appointment within 6 months of the scheduled date.
Results: One hundred and eighty-one eyes of 94 patients were included.
Purpose: Clinical trial cohorts frequently differ demographically from the overall population receiving treatment for the condition under study. Our study describes the racial, ethnic, and gender composition of the cohorts of retinal vein occlusion (RVO) macular edema (ME) clinical trials and compares this to the racial, ethnic, and gender composition of patients undergoing treatment for ME secondary to RVO from the (Intelligent Research in Sight) IRIS Registry.
Design: Retrospective observational case series Subjects: Participants in RVO-ME clinical trials that met the following inclusion criteria: conducted in the United States of America, Phase III completed, data reported between January 1, 2000, and January 1, 2020, and demographic information reported with results.
Lens-Sparing Perfluoro-Octane-Assisted External Drainage of Total Exudative Retinal Detachment in Coats' Disease.
Ophthalmic Surg Lasers Imaging Retina
August 2024
Investigation of performance of potential adsorbents for emissions mitigation in a diesel generator.
Environ Sci Pollut Res Int
July 2024
Globally, the release of greenhouse gases primarily carbon dioxide (CO) emissions to our Earth's surface has climbed by about 45% to its present atmospheric concentration rate of 420 parts per million (ppm) during the industrial era. An unprecedented rise in atmospheric CO concentration has been claimed to lead to significant factors such as global warming potential (GWP) and climate change effects. An increase in atmospheric CO concentrations is a serious threat to the environment.
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- - Chronic stress from long-term emotional pressure can lead to reproductive dysfunction, and this study explores how chronic unpredictable stress (CUS) affects reproductive neuropeptides and sperm quality in rats.
- - The experiment involved 16 rats split into control and CUS-induced groups, with various behavioral and physiological assessments conducted over 28 days, revealing significant hormonal changes and altered behaviors in the stressed group.
- - Results showed increased levels of corticotropin-releasing hormone and weakened sperm quality in CUS rats, leading to abnormal testis morphology and disrupted reproductive functions, indicating a strong impact of chronic stress on reproduction.