Publications by authors named "M Sittinger"

Article Synopsis
  • Hybrid scaffolds combining different biomaterials show promise for musculoskeletal tissue engineering, but there is a need for better in vitro systems to study their biological interactions.
  • The researchers developed a novel, scalable clamp culture system using 3D-printed polymer and hydrogel, providing mechanical stability while allowing for analysis of cell and material interactions.
  • This system demonstrated favorable results in cell viability and osteogenic differentiation after 14 days of culture, indicating its potential for advancing tissue engineering research and biomaterial development.
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Insect monitoring is essential to design effective conservation strategies, which are indispensable to mitigate worldwide declines and biodiversity loss. For this purpose, traditional monitoring methods are widely established and can provide data with a high taxonomic resolution. However, processing of captured insect samples is often time-consuming and expensive, which limits the number of potential replicates.

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Photochemical additive manufacturing technologies can produce complex geometries in short production times and thus have considerable potential as a tool to fabricate medical devices such as individualized patient-specific implants, prosthetics and tissue engineering scaffolds. However, most photopolymer resins degrade only slowly under the mild conditions required for many biomedical applications. Herein we report a novel platform consisting of amino acid-based polyphosphorodiamidate (APdA) monomers with hydrolytically cleavable bonds.

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Background: Tissue defects in the annulus fibrosus (AF) due to intervertebral disc (IVD) degeneration or after nucleodiscectomy have little self-healing capacity. To prevent progressive degeneration of the IVD, the AF must be repaired. Biological closure has not yet been achieved and is a challenge for the research community.

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