Predictors of Recurrence After Curative Surgery for Stage I Colon Cancer: Retrospective Cohort Analysis of the Italian Society of Surgical Oncology Colorectal Cancer Network Collaborative Group.

Objective: The aim of this study is to provide solid evidence to update the management of stage I colon cancer (CC) after surgery.

Background: Given the low risk of recurrence of stage I CC, some international guidelines do not recommend intensive follow-up after surgery. However, data on the actual incidence, risk factors, and site of recurrences are scarce.

The Da Vinci Robot, a Promising Yet Underused Minimally Invasive Tool for Spine Surgery: a Scoping Review of its Current Role and Limits.

Background: The Da Vinci robot ® (DVR), released in the early 2000s, provided a set of innovation aiming at pushing minimally invasive surgery forward. Its stereoscopic magnified visualization camera, motions that exceed the natural range of the human hand, or tremor reduction enhanced the surgeon's skills and added value in many surgical fields.

Objective: To map the current use of the DVR in spine surgery, identify gaps, address its limits and future perspectives.

A comprehensive analysis framework for evaluating commercial single-cell RNA sequencing technologies.

This study examined nine prominent commercially available single-cell RNA sequencing (scRNA-seq) kits across four technology groups. Each kit was characterized using peripheral blood mononuclear cells (PBMCs) from a single donor, which enabled consistent assessment of factors such as analytical performance, protocol duration and cost. The Chromium Fixed RNA Profiling kit from 10× Genomics, with its probe-based RNA detection method, demonstrated the best overall performance.

Comparing remote programming of cochlear implants using two methods: portable laptop and remote hosted site.

Objectives: Compare two remote programming methods as a clinical service for user satisfaction, ease of use, preparation time and accessibility.

Method: Method 1 (Portable Laptop): A 'Programming Kit' including laptop was shipped to cochlear implant users' homes ( = 20). The audiologist at the implant center used remote desktop control of this laptop to adjust subjects' speech processors.

Borylated Monosaccharide 3-Boronic-3-deoxy-d-galactose: Detailed NMR Spectroscopic Characterisation, and Method for Spectroscopic Analysis of Anomeric and Boron Equilibria.

Drug leads with a high Fsp index are more likely to possess desirable properties for progression in the drug development pipeline. This paper describes the first detailed NMR analysis of the borylated intermediate 3-deoxy-3-boronodiethanolamine-1,2:5,6-di--isopropylidene-α-d-galactofuranose and of the corresponding free monosaccharide analogue 3-boronic-3-deoxy-d-galactose in the early stage of the concurrent equilibrium processes of mutarotation and borarotation. A discussion of all potential equilibria is also presented alongside a comparison with relevant B-NMR data available from the scientific literature and our own library.