Publications by authors named "M Shirano"
A 65-year-old woman with Multiple Sclerosis treated with fingolimod developed headaches and convulsions. Cerebrospinal fluid (CSF) culture indicated . A literature review of 20 cases of cryptococcal meningitis indicated that headache was the most common initial symptom, and all cases were positive for serum and/or CSF cryptococcal antigens.
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- Liver disease is a major issue for people with HIV, particularly those also infected with hepatitis B (HBV) and hepatitis C (HCV), prompting a study on the prevalence and management of these conditions in Japan.
- The study analyzed data from 811 individuals on antiretroviral therapy, revealing that a significant number had chronic HBV (6.5%) and were inadequately screened for liver health, with low rates of abdominal ultrasound and tumor marker testing.
- The findings highlight serious gaps in hepatitis management for people living with HIV in Japan, indicating a need for better adherence to clinical guidelines and more integrated care approaches.
Article Synopsis
- The study investigates the effectiveness and patient satisfaction of long-acting antiretroviral therapy (ART) using cabotegravir (CAB) and rilpivirine (RPV) for individuals living with HIV who switched from conventional treatments.
- Thirty-eight male participants were monitored for 44 weeks after switching, with results showing that all maintained viral suppression and experienced increased treatment satisfaction.
- Additionally, the method demonstrated a small decrease in creatinine levels while lipid and glucose profiles remained stable, suggesting long-acting ART may enhance both health outcomes and patient well-being.
Article Synopsis
- International travel increases the risk of sexually transmitted infections (STIs) due to factors like more sexual opportunities and the appeal of the sex industry.
- A study in Japan from October 2017 to December 2022 found that out of 4,545 travel-related illnesses, only 52 (1.1%) were STIs, predominantly affecting males with a median age of 31.
- The most common STIs reported were HIV (17%), genital herpes (13%), syphilis (13%), and gonorrhea (12%), highlighting the need for greater awareness and vaccination to prevent these infections.