In silico and in vivo experiment of soymilk peptide (tetrapeptide - FFYY) for the treatment of hypertension.

Enzyme-Treated Soymilk (ETS) was produced from Commercial Soymilk (CSM) with the treatment of proteinase PROTIN SD-NY10 (Bacillus amyloliquefaciens). Previously, we have isolated novel peptides from ETS but data related to isolated-peptides are scant. In this study, bio-informatics and in vivo analysis of isolated-peptides showed strong binding affinity to the active site of the Angiotensin Converting Enzyme (ACE).

Novel angiotensin I-converting enzyme inhibitory peptides derived from soya milk.

Inhibitors of angiotensin I-converting enzyme (ACE) are useful in treating hypertension, and many have been derived from food products, including soybeans. Using the industrial protease PROTIN SD-NY10, we developed a processed soya milk (PSM) with enhanced ACE inhibitory activity. The ACE inhibitory activity of PSM (IC(50)=0.

[Left traumatic diaphragmatic hernia in the postoperative state of lung cancer: report of a case].

We report a case of left traumatic diaphragmatic hernia in the postoperative state of the lung cancer. A 68-year-old man underwent video-assisted partial resection of the left lung for lung cancer. One year after the operation, he experienced an accident of falling from a tree.

Reduplicative paramnesia after a right frontal lesion.

Objective: To report a case of reduplicative paramnesia after a focal lesion localized in the right frontal subcortical region.

Background: It is suggested that a right frontal subcortical lesion alone may be sufficient to cause cognitive disturbance that can develop into reduplicative paramnesia. Clinical data have been scarce.