Publications by authors named "M Shikano"
Article Synopsis
- * The study created a new F-DES, [TMA]F·3.5[1,3-DMU], which has a high fluoride concentration and an electrochemical window of 3.1 V, significantly better than other F-DESs like [TMA]F·3.5[EG] which only had 1.9 V.
- * This new solvent also showed much higher ionic conductivity—two orders of magnitude greater than another variant—due to the unique hydrogen bonding of its components, making it a promising option for electrochemical fluorination applications. *
Routine vaccinations help prevent the outbreak and spread of infectious diseases; however, it can take up to ten years from vaccine approval to introduction into routine vaccination schedules in Japan. Here, we investigate the information required to introduce an approved vaccine into routine vaccination schedules and the reasons why it takes so long. Based on the published data of the Immunization and Vaccine Committee of the Health Science Council, we set out to explore ways to facilitate discussion on this topic.
View Article and Find Full Text PDFThis study estimated the incidence of moderate-to-severe drug-induced interstitial lung disease (ILD) among patients with breast cancer in Japan. We analyzed a large nationwide database of patients with breast cancer treated with anticancer therapies between 2009 and 2022. ILD was identified using diagnostic codes and treatment records.
View Article and Find Full Text PDFIn the past few years, there have been several instances of illicit pharmaceutical manufacturing in Japan, and there is a growing awareness of the importance of corporate compliance and pharmaceutical manufacturing and quality controls. One cause of illicit manufacturing is the inadequate development of quality culture. This study focuses on the degree of quality culture development in Japanese pharmaceutical companies manufacturing generic drugs.
View Article and Find Full Text PDFObjective: To comprehensively elucidate the current landscape of decentralised clinical trials (DCTs) and identify notable aspects that can facilitate DCT implementation.
Design: Cross-sectional analysis.
Setting: Data were extracted using selected DCT-specific search terms on 4 June 2022, from the ClinicalTrials.