Ossification patterns of the C1 (atlas) and C2 (axis) vertebrae children.

Purpose: This retrospective study aimed to assess ossification patterns and synchondrosis fusion timelines of the C1 and C2 vertebrae in pediatric age group, to help differentiate injuries from normal variations and serve as a guide when evaluating incompletely fused synchondrosis.

Materials And Methods: The study analyzed 432 CT examinations of children aged 0-72 months, conducted at a single institution between January 2010 and January 2018. The focus was assessment of the visibility and fusion of the three ossification centers and three synchondroses of the atlas, and six ossification centers and four synchondroses of the axis, based on age.

Evaluation of modified essay questions (MEQs) as an assessment tool in third-year medical students' modular summative assessment.

Aim: Whether case-based modified essay questions (MEQs) are crucial to summative assessment in medical curriculum is still debatable. The current study aimed to evaluate third-year medical students' performance in case-based MEQs and multiple-choice questions (MCQs) in summative assessment in the endocrine module.

Methods: Students' scores in mid and final module MEQs and MCQs were analyzed over four successive years from 2018/2019 to 2021/2022, where comparisons were made between students' scores in MEQs and MCQs, and between scores of students of different categories.

Exploring the cross-cultural validity of attachment theory: a study of Egyptian mother-child dyads using the Strange Situation Procedure.

Given the dearth of literature on attachment theory in the Arab world, this study explores the cross-cultural validity of attachment theory within an Egyptian sample of 60 mother-child dyads through the Strange Situation Procedure (SSP). The study examines the applicability of attachment theory's universality, normativity, and secure base hypotheses, as well as the prevalence and manifestations of insecurity in an Egyptian sample. The findings supported attachment theory's universality, normativity and secure base hypotheses, while simultaneously pointing towards cultural variations in attachment manifestations.

Somatic Recombination Between an Ancient and a Recent Gene Variant Is Associated with the NOTCH2 Gain-of-Function Phenotype in Chronic Lymphocytic Leukemia.

Constitutively active NOTCH2 signaling is a hallmark in chronic lymphocytic leukemia (CLL). The precise underlying defect remains obscure. Here we show that the mRNA sequence coding for the NOTCH2 negative regulatory region (NRR) is consistently deleted in CLL cells.

Evaluation of the effect of a communication skills course on medical students' attitude towards patient-centered care: a prospective study.

Background: This study aims to examine whether a communication skills course (Early Clinical Exposure-ECE) might support shaping medical students' attitudes towards patient-centered care at Taibah University, Saudi Arabia. Attitudes were measured before and after the course using the Patient Practitioner Orientation Scale (PPOS), which assesses students' orientation towards patient-centeredness.

Methods: This prospective observational study collected data at two points: the start of year two and the start of year four from the same cohort.