Publications by authors named "M Shayestehpour"
Ebola virus (EBOV) is a life-threatening and virulent pathogen that kills approximately 90 percent of infected individuals. Nowadays, microRNAs (miRNAs) have become a promising option for more efficient screening, diagnosis, monitoring, and therapy of numerous diseases such as cancer, stroke, Alzheimer's, and viral infections. Recent studies have revealed the role of EBOV and host-encoded miRNAs in Ebola virus disease (EVD), opening an avenue for developing novel drugs against EVD and diagnostic panels for EBOV infection.
View Article and Find Full Text PDFArticle Synopsis
- - The study explored the potential link between human herpesvirus type 6 (HHV-6) and systemic lupus erythematosus (SLE) by comparing infection rates in 60 SLE patients and 60 healthy individuals.
- - Results showed that HHV-6 was found in 20% of SLE patients versus 13.3% of healthy individuals, but no significant correlation was established between HHV-6 infections and SLE or its symptoms.
- - Despite a slightly higher prevalence of HHV-6 in SLE patients, the findings do not support a strong connection between the virus and the disease, indicating that further research is needed to clarify the role of HHV-6 in SLE
Background And Objectives: Human herpes virus type 1 (HSV-1) is a neurotropic pathogen that is infected more than 70% of the world population. The increasing of viral resistance to antiviral drugs and the emergence of side effects has motivated researchers to study the use of probiotics as new antiviral agents. The aim of the present study was to study for the first time the potential antiviral activity of supernatant against HSV-1.
View Article and Find Full Text PDFBackground: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious virus that uses angiotensin converting enzyme 2 (ACE2), a pivotal member of the renin-angiotensin system (RAS), as its cell-entry receptor. Another member of the RAS, angiotensin II (Ang II), is the major biologically active component in this system. There is growing evidence suggesting that serum miRNAs could serve as prognostic biomarkers for SARS-CoV-2 infection and regulate ACE2 expression.
View Article and Find Full Text PDFPurpose: This study aimed to investigate the effect of Curcumin nanoparticles and alcoholic extract of Falcaria vulgaris on the growth rate, biofilm, and gene expression in Pseudomonas aeruginosa isolated from burn wound infection.
Methods: The alcoholic extract of Falcaria vulgaris was purchased from Pasargad Company. Curcumin nanoparticles were synthesized.