Holter ECG monitoring and platelets characteristics in patients with coronary artery disease and atrial fibrillation.

Objective: Aim: To check the relationships between platelet characteristics and Holter ECG monitoring results in patients with atrial fibrillation (AF) and coronary artery disease (CAD).

Patients And Methods: Materials and Methods: 300 investigated patients were separated into three groups: I (CAD) - 149 patients with CAD without arrhythmias, II (CAD and AF) - 124 patients with CAD and AF paroxysm, and the control group (CG) - 27 patients without CAD and arrhythmias.

Results: Results: In the II group was detected an increase in mean platelet volume (MPV) (9.

Development of pharmacovigilance system in Ukraine: first results.

The article is devoted to the establishment and development of the National Pharmacovigilance system in Ukraine. A drug safety centre of Ukraine started to form a pharmacovigilance system in 1996. It has been operating on a regular basis since 2000 and now provides the regulatory services that include data collection and analysis, database management, education, international contacts, and the publication and dissemination of information.