In the present study, the mechanisms involved in scopolamine-induced memory impairment have been investigated. The molecular events that take place during memory mostly include mechanisms that are seen in the acquisition phase. Results showed that one of the mechanisms of memory destruction caused by scopolamine, in addition to weakening the cholinergic system, is the indirect effect of scopolamine on other neurotransmitter systems, including the glutamatergic system.
View Article and Find Full Text PDFIn this study, the role of gummosin in improving memory in the scopolamine memory impairment model was systematically examined. Memory and learning are the most developed and complex functions of the nervous system. Learning is the acquisition of new information that occurs as a change in behavior, and memory is the ability to store and retrieve learned information.
View Article and Find Full Text PDFThe fabrication of earth-abundant electrocatalysts capable of facilitating hydrogen evolution reactions (HER) is essential for creating sustainable hydrogen fuel by water splitting. Here, we present a one-pot hydrothermal approach for producing aluminum and phosphorus co-doped NiS/NiS/WS heterostructure hybrid frameworks on nickel foam. The optimal Al and Al, P/NiWS-b@NF catalyst exhibits high HER activity with overpotentials of 139 and 227 mV at current densities of 10 and 50 mA cm, respectively, thanks to the synergistic effect of the various constituents of the catalyst.
View Article and Find Full Text PDFBackground: Hypertension (HTN) is a common chronic health problem with many complications and high morbidity rates. This study aimed to describe the HTN pathway, to assess the performance of screening and registration programs, to explore the challenges and suggest solutions for those challenges.
Materials And Methods: This study was conducted in primary care centers in the Aseer region, Saudi Arabia, at the end of 2022.