Publications by authors named "M Senekal"

Given the high prevalence of overweight and obesity amongst educators, this study investigated the feasibility of the 16-week Health4LIFE weight loss intervention for primary school educators living with overweight/obesity in low-income settings in Cape Town, South Africa. The research comprised two sub-studies, a pilot randomised controlled trial testing the intervention (10 intervention, = 79 and 10 control schools, = 58), and an investigation of the perceptions of participating educators and principals. Feasibility outcomes included reach, applicability, acceptability, implementation integrity, and a hypothesis-generating signal of effect on lifestyle factors and weight.

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A review of the literature showed that there were only a few studies that reported on the dietary patterns of children in South Africa. The aim of the present study was to characterise the dietary patterns of children aged 1-<10 years who were studied during the Provincial Dietary Intake Survey (PDIS) in 2018 and to investigate the socio-demographic predictors thereof, as well as the associations with stunting and overweight/obesity. Dietary pattern analysis was conducted within three age groups, namely 1-<3-year-olds, 3-<6-year-olds, and 6-<10-year-olds using iterated principal factor analysis with varimax rotation and 24 h recall data from the PDIS.

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Hearing loss places a substantial burden on medical resources across the world and impacts quality of life for those affected. Further, it can occur peripherally and/or centrally. With many possible causes of hearing loss, there is scope for investigating the underlying mechanisms involved.

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Prenatal alcohol exposure (PAE) causes growth restriction that worsens in the first year of life. However, the roles of postnatal nutrition in fetal alcohol growth restriction and the impact of postnatal alcohol exposure via breastmilk on growth remain unknown. We aimed to compare infant feeding practices during the first 6.

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Article Synopsis
  • A study investigated the effects of B vitamins and homocysteine on various health outcomes using data from nearly 386,000 UK Biobank participants, revealing mixed results in past research into their health impacts.
  • The research included a phenome-wide association study (PheWAS) to find associations between B vitamins, homocysteine, and numerous diseases, followed by Mendelian randomization (MR) to confirm causality for certain outcomes.
  • Out of 1117 tested phenotypes, 32 associations were found significant, with three showing causality: higher vitamin B6 linked to lower kidney stone risk, and higher homocysteine associated with increased risks of hypercholesterolemia and chronic kidney disease. *
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