is a ubiquitous saprophytic fungus. Inhalation of spores can lead to Invasive Aspergillosis (IA) in people with weakened immune systems. The use of triazole antifungals with the demethylation inhibitor (DMI) mode of action to treat IA is being hampered by the spread of DMI-resistant "ARAf" (azole-resistant ) genotypes.
View Article and Find Full Text PDFEffects of plant cropping measures on toxin production were investigated. The use of the plough reduced the DON level by 71%. Additionally, the choice of less sensitive varieties, as well as an adequate nitrogen fertilization showed a significant reduction of the DON content in grain.
View Article and Find Full Text PDFZ Naturforsch C J Biosci
January 1997
In the course of our search for new biologically active metabolites, lachnellin A (1), a metabolite with high cytotoxic and antimicrobial activities, the structurally related lachnellins B, C and D (3, 4, 7), and naphthalene-1,3,8-triol (8), an inhibitor of malate synthase (EC 4.1.3.
View Article and Find Full Text PDFTyromycin A, a new inhibitor of leucine and cysteine aminopeptidases has been isolated from mycelial cultures of the basidiomycete Tyromyces lacteus (Fr.) Murr. Its structure was established as 1,16-bis-[4-methyl-2,5-dioxo-3-furyl]hexadecane (1) by spectral analysis and transformation into ester and imide derivatives.
View Article and Find Full Text PDFFolia Histochem Cytobiol
April 1987
Cytochemical characterization of mucosubstances of chick glanular stomach (proventriculus) changes from 15 days of development to postnatal and adult stages was studied. To corroborate these data cytochemical, ultrastructural and ultracytochemical study of chick embryo proventriculus from 7 to 20 days of development was performed. At the 7th day several layers of undifferentiated cells formed an epithelium which covered the walls of the glandular stomach.
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