Publications by authors named "M Sellers"

Article Synopsis
  • Coccidioidomycosis is a serious fungal infection that can be transmitted through organ transplantation, with a review of cases from 2013 to 2022 revealing significant risks.
  • Seven deceased donors transmitted the infection to eight recipients, resulting in a 40% infection rate among organ recipients.
  • The study highlights the importance of thorough donor evaluations and antifungal treatment to reduce the high mortality associated with these infections post-transplant.
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Article Synopsis
  • The text discusses the challenges and potential of using organs from donors who die after cardiac arrest (DCD), highlighting that while there’s a significant need for donor organs, the outcomes for these organs have been historically poor.
  • Normothermic regional perfusion (NRP) is introduced as a technique that can enhance the outcomes and increase the use of DCD organs, but there is inconsistency in how different US organ procurement organizations (OPOs) implement it.
  • A survey of 55 OPOs revealed variations in NRP practices, with 49 OPOs having conducted NRP cases; most respondents expressed a need for standardized guidelines to improve the consistency and effectiveness of NRP procedures.
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The Surveillance, Epidemiology, and End Results (SEER) Program, an authoritative source of cancer statistics in the United States, has been funded by the National Cancer Institute (NCI) since 1973. The goals of SEER include measuring the cancer burden in the United States, making the results available, and supporting cancer research. These goals render products that serve as resources for different audiences, such as cancer registrars, researchers, and the public.

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Background: Normothermic regional perfusion (NRP) has emerged as a vital technique in organ procurement, particularly in donation after circulatory death (DCD) cases, offering the potential to optimize organ utilization and improve posttransplant outcomes. Recognizing its significance, the American Society of Transplant Surgeons (ASTS) convened a work group to develop standardized recommendations for abdominal NRP in the United States.

Methods: The workgroup, comprising experts in NRP, DCD, and transplantation, formulated recommendations through a collaborative process involving revisions and approvals by relevant committees and the ASTS council.

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Background: Better access to direct-acting antiviral (DAA) therapy has broadened the utilization of hepatitis C virus (HCV) nucleic acid testing (NAT) positive organs with excellent outcomes. However, DAA therapy has been associated with hepatitis B virus (HBV) reactivation.

Aim: To determine the risk of HBV transmission or reactivation with utilization of HBV core antibody positive (HBcAb+) and HCV NAT positive (HCV+) organs, which presumably required DAA therapy.

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