Publications by authors named "M Sekine"
Article Synopsis
- Cervical cancer screening rates in Japan are low, making prenatal visits an important opportunity for women to undergo cervical cytology tests during pregnancy, according to this study.
- The study analyzed data from 2,725 participants, revealing that certain factors such as smoking, younger age, lower education levels, and specific sampling methods were linked to higher rates of abnormal cervical results (ASC-US).
- Results showed that nearly 40% of participants with abnormal results thought they had “no abnormalities,” highlighting the need for better patient education and follow-up for those with detected issues.
Background: To evaluate the effect of the type and codetection of respiratory viruses on admission requirements among children with respiratory infections in the post-COVID-19 pandemic era.
Methods: In this retrospective study, we analyzed patients with acute respiratory symptoms using FilmArray® Respiratory Panel between December 2020 and March 2024. The viruses were classified into eight groups: adenovirus, seasonal coronavirus, human metapneumovirus, human rhinovirus/enterovirus, influenza virus, parainfluenza virus, respiratory syncytial virus, and severe acute respiratory virus coronavirus-2.
Article Synopsis
- * A nationwide case-control study aimed to estimate the vaccine's effectiveness against advanced cervical lesions (like CIN3+) among women aged 20-26 from 2013 to 2020, revealing a significant risk reduction for vaccinated individuals.
- * Results showed that vaccinated women had an odds ratio of 0.14 for developing CIN3 or higher compared to unvaccinated women, indicating an 86% effectiveness of the HPV vaccine; notably, none of the squamous cell carcinoma cases were from vaccinated women.
Background: Peripheral inflammation is often associated with depressive disorders, and immunological biomarkers of depression remain a focus of investigation.
Methods: We performed RNA-seq analysis of RNA transcripts of human peripheral blood mononuclear cells from a case-control study including subjects with self-reported depression in the pre-symptomatic state of major depressive disorder and analyzed differentially expressed genes (DEGs) and the frequency of intron retention (IR) using rMATS.
Results: Among the statistically significant DEGs identified, the 651 upregulated DEGs were particularly enriched in the term "bacterial infection and phagocytosis", whereas the 820 downregulated DEGs were enriched in the terms "antigen presentation" and "T-cell proliferation and maturation".
Aim: The aim of this study was to develop quantitative outcome indicators for psychiatric training programs integrated into the General Medicine In-Training Examination (GM-ITE) and to investigate which characteristics correlate with high scores in psychiatry.
Methods: A nationwide cross-sectional study was conducted over 3 fiscal years (2021-2023). An anonymous online questionnaire was distributed to postgraduate year 1 and 2 residents who completed the GM-ITE.