Clinical utility of periodic reinterpretation of CNVs of uncertain significance: an 8-year retrospective study.

Background: Array-CGH is the first-tier genetic test both in pre- and postnatal developmental disorders worldwide. Variants of uncertain significance (VUS) represent around 10~15% of reported copy number variants (CNVs). Even though VUS reanalysis has become usual in practice, no long-term study regarding CNV reinterpretation has been reported.

Laser-induced graphene non-enzymatic glucose sensors for on-body measurements.

Non-enzymatic glucose sensors outperform enzymatic ones in terms of cost, sensitivity, stability, and operating duration. Though highly sensitive, it is still desirable to further improve the sensitivity of non-enzymatic glucose sensors to detect a trace amount of glucose in sweat and other biofluids. Among the demonstrated effective approaches using bimetals or 3D porous structures, the porous laser-induced graphene (LIG) on flexible polymers showcases good conductivity and a simple fabrication process for the integration of sensing materials.

Stretchable wideband dipole antennas and rectennas for RF energy harvesting.

The ultimate application of bio-integrated, stretchable electronics hinges on the indispensable modules of stretchable wireless data transmission and power supplies. While radiofrequency (RF) antennas and rectennas could enable wireless communication and RF energy harvesting in the far-field, their performance deteriorates because of the frequency detuning from mechanical deformations. Here, stretchable wideband antennas and rectennas are introduced to robustly operate and combine received RF power over their wideband upon mechanical deformations.

Consequences of joint action: Entanglement with your partner.

Primates are expert tool users because they can adapt their body schemas to form a hand-tool joint representation that affords effective wielding. Here we extend the scope of this mechanism by proposing that humans are experts in social tasks because they can adjust their body schemas to incorporate the kinematics of partners, thus forming an interpersonal joint body schema. Participants engaged with a confederate in a 2-handed sawing task requiring each to use 1 hand.