The amino acid permease contributes to tomato growth and salt tolerance by mediating branched-chain amino acid transport.

Branched-chain amino acids (BCAAs) are essential amino acids in tomato () required for protein synthesis, which also modulate growth and abiotic stress responses. To date, little is known about their uptake and transport in tomato especially under abiotic stress. Here, the tomato () gene was identified as an amino acid transporter that restored mutant yeast cell growth on media with a variety of amino acids, including BCAAs.

Evaluating AI performance in nephrology triage and subspecialty referrals.

Artificial intelligence (AI) has shown promise in revolutionizing medical triage, particularly in the context of the rising prevalence of kidney-related conditions with the aging global population. This study evaluates the utility of ChatGPT, a large language model, in triaging nephrology cases through simulated real-world scenarios. Two nephrologists created 100 patient cases that encompassed various aspects of nephrology.

Tunable optical nonreciprocity in double-cavity optomechanical system with nonreciprocal coupling.

We propose a double-cavity optomechanical system with nonreciprocal coupling to realize tunable optical nonreciprocity that has the prospect of making an optical device for the manipulation of information processing and communication. Here we investigate the steady-state dynamic processes of the double-cavity system and the transmission of optical waves from opposite cavity directions. The transmission spectrum of the probe field is presented in detail and the physical mechanism of the induced transparency window is analyzed.

CHMP4C promotes pancreatic cancer progression by inhibiting necroptosis via the RIPK1/RIPK3/MLKL pathway.

Introduction: Pancreatic cancer (PC) cannot currently be completely cured and has a poor prognosis. Necroptosis is a distinct form of regulated cell death that differs from both necrosis and apoptosis. Understanding the role of necroptosis during PC progression would open new avenues for targeted therapy.