Basement membranes are among the most widespread, non-cellular functional materials in metazoan organisms. Despite this ubiquity, the links between their compositional and biophysical properties are often difficult to establish due to their thin and delicate nature. In this article, we examine these features on a molecular level by combining results from proteomics, elastic, and nanomechanical analyses across a selection of human basement membranes.
View Article and Find Full Text PDFThe Descemet's membrane (DM) and the lens capsule (LC) are two ocular basement membranes (BMs) that are essential in maintaining stability and structure of the cornea and lens. In this study, we investigated the proteomes and biomechanical properties of these two materials to uncover common and unique properties. We also screened for possible protein changes during diabetes.
View Article and Find Full Text PDFThis paper develops an atmospheric state estimator based on inertial acceleration and angular rate measurements combined with a vehicle aerodynamic model. The approach utilizes the navigation state of the vehicle to recast the vehicle aerodynamic model to be a function solely of the atmospheric state. Force and moment measurements are based on vehicle sensed accelerations and angular rates.
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