Publications by authors named "M Scharf"
Background: Telehealth is now a necessary component of health care delivery, and its use among health care professionals was accelerated by the COVID-19 pandemic.
Problem: Nurse practitioner (NP) programs generally incorporate telehealth competencies within their curriculum, preparing NPs to effectively deliver telehealth and improve health outcomes.
Approach: We developed and implemented a telehealth blueprint to enhance telehealth content within our clinical Doctor of Nursing Practice (DNP) program guided by the Four Ps of the Telehealth Framework planning, preparing, providing, and performance evaluation.
Article Synopsis
- - The COVID-19 pandemic increased parental burnout and negatively impacted psychological well-being, but not all parents experienced the same level of stress during this time.
- - A study of 281 Israeli parents during lockdown explored how optimism, humor, and resilience acted as protective factors against parental burnout.
- - Results showed that resilience, optimism, and humor were linked to lower parental burnout, although these factors didn't affect stress perception; the study highlights the importance of fostering positive attitudes during stressful periods.
Novel assessment of CPAP adherence data reveals distinct diurnal patterns.
J Clin Sleep Med
November 2024
Study Objectives: Obstructive sleep apnea (OSA) is a prevalent condition effectively treated by continuous positive airway pressure (CPAP) therapy. CPAP adherence data, routinely gathered in clinical practice, include detailed information regarding both duration and timing of use. The purpose of the present study was to develop a systematic way to measure the diurnal pattern of CPAP adherence data and to see if distinct patterns exist in a clinical cohort.
View Article and Find Full Text PDFGlutathione S-transferases (GSTs) are an important class of enzymes that facilitate the conjugation of reduced glutathione (GSH) with electrophilic substrates, including some insecticides. Two inhibitors of GSTs, ethacrynic acid (EA) and diethyl maleate (DEM), are often used as diagnostic tools to implicate GST involvement in insecticide resistance, but their modes of action against insect GSTs are largely assumed based on mammalian studies. In mammalian studies, there are two proposed mechanisms of inhibition of GST function by EA and DEM: 1) scavenging or "depleting" cytosolic GSH through non-enzymatic conjugation, and 2) inhibition of GST activity directly by the inhibitor-GSH conjugate (EA-SG and DEM-SG).
View Article and Find Full Text PDFArticle Synopsis
- The study evaluates the effectiveness of the new EUROLINE Neurologic Syndrome 15 Ag (IgG) test, which adds three new antigens to the existing EUROLINE Paraneoplastic Neurologic Syndrome 12 Ag test.
- The analysis involved testing 194 diagnosed samples and over 100 healthy controls, confirming high sensitivity (89-100%) and specificity (≥99%) for the autoantibodies associated with neurological disorders.
- The findings suggest that this new diagnostic tool can improve the detection of various neuronal autoantibodies, particularly by identifying double positivity for anti-CDR2 and anti-CDR2L, which is linked to paraneoplastic cerebellar degeneration.