Publications by authors named "M Scatena"
Introduction: The use of cardiopulmonary bypass (CPB) can induce sterile systemic inflammation that contributes to morbidity and mortality, especially in children. Patients have been found to have increased expression of cytokines and transmigration of leukocytes during and after CPB. Previous work has demonstrated that the supraphysiologic shear stresses existing during CPB are sufficient to induce proinflammatory behavior in non-adherent monocytes.
View Article and Find Full Text PDFIntroduction: Heterotopic ossification (HO) occurs following orthopedic trauma, spinal cord injuries, brain trauma and limb amputations. Once symptomatic, HO causes pain, limited mobility and decreased quality of life. Current treatments are limited and have significant complications with high recurrence rates, underscoring the need for improved therapeutic interventions.
View Article and Find Full Text PDFArticle Synopsis
- The study examines the bioavailability of toxic elements like As, Hg, Tl, and Pb in soil and their potential risks to the environment and human health, particularly in areas affected by mining.
- It focuses on the distribution of these elements in the Castanea sativa (chestnut) plant across two different sites in Italy, with similar conditions but varying soil PTE levels.
- Findings indicate that chestnut trees can effectively monitor these contaminants, showing tissue-specific patterns of element accumulation, with Thallium and Mercury present in all tissues, while Arsenic is found in leaves, wood, and nuts, and Lead is only in the bark.
This protocol details the propagation and passaging of human iPSCs and their differentiation into osteoclasts. First, iPSCs are dissociated into a single-cell suspension for further use in embryoid body induction. Following mesodermal induction, embryoid bodies undergo hematopoietic differentiation, producing a floating hematopoietic cell population.
View Article and Find Full Text PDF